Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

SMAD4 [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

componentOf

consumedByEvent

[FailedReaction:R-HSA-3315483] Phosphorylated SMAD2/3 MH2 Domain Mutants do not bind SMAD4 - Homo sapiens
[Reaction:R-HSA-170847] Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 - Homo sapiens
[Reaction:R-HSA-170847] Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 - Homo sapiens
[Reaction:R-HSA-170847] Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 - Homo sapiens
[Reaction:R-HSA-201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad - Homo sapiens

created [InstanceEdit:170836] Jassal, B, 2006年01月18日 10:19:52

dbId 170862

displayName SMAD4 [cytosol]

endCoordinate 552

inDisease false

inferredTo

maxDepth 1

modified [InstanceEdit:2176484] Orlic-Milacic, M, 2012年04月02日

name

SMAD4
Co-SMAD
Mothers against decapentaplegic homolog 4

producedByEvent

[Reaction:R-HSA-870437] USP9X (FAM) deubiquitinates SMAD4 - Homo sapiens

referenceEntity [ReferenceGeneProduct:uniprot:Q13485] UniProt:Q13485 SMAD4

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-170862

startCoordinate 1

updateTrackers

Referrals

(updatedInstance)

(input)

(normalEntity)

[EntityFunctionalStatus:3311016] loss_of_function of SMAD4 MH2 domain mutants

(hasComponent)

(output)

[Reaction:R-HSA-870437] USP9X (FAM) deubiquitinates SMAD4

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