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Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer Show undefined attributes

authored

[InstanceEdit:1606299] Shamovsky, V, 2011年09月21日

category binding

compartment

[Compartment:74700] endosome membrane

created [InstanceEdit:1679095] Shamovsky, V, 2011年10月19日

dbId 1679098

displayName Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer

edited

[InstanceEdit:2129343] Shamovsky, V, 2012年02月19日

eventOf

[Pathway:R-HSA-168138] Toll Like Receptor 9 (TLR9) Cascade - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

name

Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer

orthologousEvent

output

[Complex:R-HSA-1679094] N-ter TLR9 dimer:unmethylated CpG DNA [endosome membrane]

precedingEvent

[Reaction:R-HSA-1678981] TLR9 processing at neutral pH - Homo sapiens

regulatedBy

[PositiveRegulation:R-HSA-1679582] Positive regulation by 'EEA1:EEA1 [endosome membrane]'

releaseDate 2012年03月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:2121211] Gillespie, ME, 2012年02月09日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-1679098

summation

[Summation:1679549] TLR9 traffics to an endosomal vesicle where it is processed ...

updateTrackers

[UpdateTracker:9788398] Update Tracker - [Reaction:1679098] Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer - v42:[addLiteratureReference]

Referrals

(updatedInstance)

[UpdateTracker:9788398] Update Tracker - [Reaction:1679098] Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer - v42:[addLiteratureReference]

(hasEvent)

[Pathway:R-HSA-168138] Toll Like Receptor 9 (TLR9) Cascade

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