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Transcriptional activation of Citrate lyase monomer gene by ChREBP:MLX Show undefined attributes

category omitted

compartment

created [InstanceEdit:163728] Gopinathrao, G, 2005年05月06日 17:09:17

dbId 163770

displayName Transcriptional activation of Citrate lyase monomer gene by ChREBP:MLX

eventOf

[Pathway:R-HSA-163765] ChREBP activates metabolic gene expression - Homo sapiens

followingEvent

[Reaction:R-HSA-75848] ACLY tetramer transforms CIT to Ac-CoA - Homo sapiens

goBiologicalProcess [GO_BiologicalProcess:17788] positive regulation of transcription by RNA polymerase II

input

[EntityWithAccessionedSequence:R-HSA-9666703] ACLY gene [nucleoplasm]

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:9857474] D'Eustachio, Peter, 2024年01月05日

name

Transcriptional activation of Citrate lyase monomer gene by ChREBP:MLX

output

[Complex:R-HSA-76188] ACLY tetramer [cytosol]

precedingEvent

[Reaction:R-HSA-9856549] MLXIPL:MLX binds ACLY gene promoter - Homo sapiens

regulatedBy

[PositiveGeneExpressionRegulation:R-HSA-164421] Positive gene expression regulation by 'MLXIPL:MLX:ACLY gene [nucleoplasm]'

regulationReference

[RegulationReference:9857473] Positive gene expression regulation by 'MLXIPL:MLX:ACLY gene [nucleoplasm]' Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes.

releaseDate 2005年04月11日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-163770

summation

[Summation:179357] The ACLY (ATP citrate synthase) gene, activated by binding o...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-163765] ChREBP activates metabolic gene expression

(precedingEvent)

[Reaction:R-HSA-75848] ACLY tetramer transforms CIT to Ac-CoA

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