Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

FGFR1 N546K [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-2023414] FGFR1 N546K mutant dimer [plasma membrane] - Homo sapiens
[Complex:R-HSA-2023414] FGFR1 N546K mutant dimer [plasma membrane] - Homo sapiens

created [InstanceEdit:1614378] Rothfels, K, 2011年09月28日

crossReference

dbId 1614377

disease

displayName FGFR1 N546K [plasma membrane]

endCoordinate 822

hasModifiedResidue

[ReplacedResidue:1614376] L-asparagine 546 replaced with L-lysine

inDisease true

literatureReference

maxDepth 1

memberOf

[CandidateSet:R-HSA-2012030] FGFR1 mutants with enhanced kinase activity [plasma membrane] - Homo sapiens

modified [InstanceEdit:9962055] Matthews, Lisa, 2025年07月30日

name

FGFR1 N546K

referenceEntity [ReferenceGeneProduct:uniprot:P11362] UniProt:P11362 FGFR1

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-1614377

startCoordinate 22

summation

[Summation:1614379] weak constitutive activation of ligand independent binding b...

updateTrackers

Referrals

(updatedInstance)

(hasMember)

[CandidateSet:R-HSA-2012030] FGFR1 mutants with enhanced kinase activity [plasma membrane]

(hasComponent)

[Complex:R-HSA-2023414] FGFR1 N546K mutant dimer [plasma membrane]

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