Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

FBXW7gamma R347C [nucleoplasm] Show undefined attributes

candidateOf

[CandidateSet:R-HSA-1602341] FBXW7 R465/347C mutant [nucleoplasm] - Homo sapiens

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:1602327] Orlic-Milacic, M, 2011年09月14日

crossReference

dbId 1602331

disease

displayName FBXW7gamma R347C [nucleoplasm]

endCoordinate 589

hasModifiedResidue

[ReplacedResidue:1602322] L-arginine 347 replaced with L-cysteine

inDisease true

literatureReference

[LiteratureReference:1602315] FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

maxDepth 1

modified [InstanceEdit:3662293] Orlic-Milacic, M, 2013年06月06日

name

FBXW7gamma R347C
FBXW7gamma Arg347Cys
FBXW7-4 R347C
FBXW7 isoform 4 R347C

referenceEntity [ReferenceIsoform:uniprot:Q969H0-4] UniProt:Q969H0-4 FBXW7

referenceType ReferenceIsoform

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-1602331

startCoordinate 1

updateTrackers

Referrals

(updatedInstance)

(hasCandidate)

[CandidateSet:R-HSA-1602341] FBXW7 R465/347C mutant [nucleoplasm]

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