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Furin cleaves pro-factor X to factor X Show undefined attributes

catalystActivity

[CatalystActivity:156993] serine-type endopeptidase activity of FURIN [Golgi membrane]

category transition

compartment

created [InstanceEdit:159817] D'Eustachio, P, 2005年03月17日 16:24:57

dbId 159733

displayName Furin cleaves pro-factor X to factor X

eventOf

[Pathway:R-HSA-159782] Removal of aminoterminal propeptides from gamma-carboxylated proteins - Homo sapiens

input

[Complex:R-HSA-159744] pro-factor X [Golgi lumen]

isInDisease false

isInferred false

literatureReference

[LiteratureReference:6807230] PACE/furin can process the vitamin K-dependent pro-factor IX precursor within the secretory pathway

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Furin cleaves pro-factor X to factor X
pro-factor X -> factor X + factor X propeptide

orthologousEvent

output

precedingEvent

[BlackBoxEvent:R-HSA-159757] Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus - Homo sapiens

releaseDate 2005年06月13日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-159733

summation

[Summation:179107] Furin, associated with the Golgi membrane, cleaves pro-facto...

updateTrackers

[UpdateTracker:9783844] Update Tracker - [Reaction:159733] Furin cleaves pro-factor X to factor X - v55:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9783844] Update Tracker - [Reaction:159733] Furin cleaves pro-factor X to factor X - v55:[addLiteratureReference, modifyText]

(hasEvent)

[Pathway:R-HSA-159782] Removal of aminoterminal propeptides from gamma-carboxylated proteins

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