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Cytosolic sulfonation of small molecules
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authored
[InstanceEdit:156583] Jassal, B, 2004年11月29日 11:42:34
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:156583] Jassal, B, 2004年11月29日 11:42:34
dbId
156584
displayName
Cytosolic sulfonation of small molecules
edited
[InstanceEdit:350358] Jassal, Bijay, 2008年05月19日
eventOf
[Pathway:R-HSA-156580] Phase II - Conjugation of compounds - Homo sapiens
figure
[Figure:176583] /figures/SULT_enzyme_specificities.jpg
goBiologicalProcess
[GO_BiologicalProcess:80798] 3'-phosphoadenosine 5'-phosphosulfate metabolic process
hasDiagram
false
hasEHLD
false
hasEvent
[Reaction:R-HSA-158468] SULT1A1 dimer sulfonates PARA to PARA-SO4 - Homo sapiens
[Reaction:R-HSA-158860] SULT1A1 dimer sulfonates NHABP - Homo sapiens
[Reaction:R-HSA-158849] Phenol can form a sulfate conjugate - Homo sapiens
[Reaction:R-HSA-159358] SULT1A3,4 dimers sulfate DA to DAOS - Homo sapiens
[Reaction:R-HSA-176474] 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176585] 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP - Homo sapiens
[Reaction:R-HSA-5695964] ABHD14B hydrolyses PNPB - Homo sapiens
[Reaction:R-HSA-176646] p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176669] N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176609] cholesterol + PAPS => cholesterol sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176494] SULTs transfer (SO4)2- group to 27HCHOL - Homo sapiens
[Reaction:R-HSA-176517] SULTs transfer (SO4)2- group to PREG - Homo sapiens
[Reaction:R-HSA-176664] estrone + PAPS => estrone 3-sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176631] dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176588] lithocholate + PAPS => lithocholate sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176604] taurolithocholate + PAPS => taurolithocholate sulfate + PAP - Homo sapiens
[Reaction:R-HSA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Homo sapiens
[Reaction:R-HSA-8954262] TPST1,2 transfer SO4(2-) from PAPS to PODXL2 - Homo sapiens
[Reaction:R-HSA-8953499] IMPAD1 hydrolyses PAP to AMP - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2023年09月13日
literatureReference
[Book:76380] 9780071470513 Parkinson, A Casarett and Doull's Toxicology 5th Edn
[LiteratureReference:158870] Sulfotransferase catalyzing sulfation of heterocyclic amines
[LiteratureReference:158863] Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes
[LiteratureReference:158854] Sulfonation and molecular action
maxDepth
2
modified
[InstanceEdit:10948619] Weiser, Joel, 2025年08月27日
name
Cytosolic sulfonation of small molecules
orthologousEvent
[Pathway:R-MMU-156584] Cytosolic sulfonation of small molecules - Mus musculus
[Pathway:R-RNO-156584] Cytosolic sulfonation of small molecules - Rattus norvegicus
[Pathway:R-CFA-156584] Cytosolic sulfonation of small molecules - Canis familiaris
[Pathway:R-BTA-156584] Cytosolic sulfonation of small molecules - Bos taurus
[Pathway:R-SSC-156584] Cytosolic sulfonation of small molecules - Sus scrofa
[Pathway:R-DRE-156584] Cytosolic sulfonation of small molecules - Danio rerio
[Pathway:R-XTR-156584] Cytosolic sulfonation of small molecules - Xenopus tropicalis
[Pathway:R-GGA-156584] Cytosolic sulfonation of small molecules - Gallus gallus
[Pathway:R-DME-156584] Cytosolic sulfonation of small molecules - Drosophila melanogaster
[Pathway:R-CEL-156584] Cytosolic sulfonation of small molecules - Caenorhabditis elegans
[Pathway:R-DDI-156584] Cytosolic sulfonation of small molecules - Dictyostelium discoideum
previousReviewStatus
[ReviewStatus:9821384] two stars
releaseDate
2008年06月30日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9953101] Matthews, Lisa, 2025年05月28日
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-156584
summation
[Summation:156585] Two groups of sulfotransferease (SULT) enzymes catalyze the ...
updateTrackers
[UpdateTracker:9846983] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v82:[updateIndirectRLE]
[UpdateTracker:9788806] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v40:[updateContainedRLE]
[UpdateTracker:9784195] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v54:[addHasEvent, updateContainedRLE]
[UpdateTracker:9790400] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v33:[addHasEvent]
[UpdateTracker:9789480] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v38:[updateContainedPathway]
[UpdateTracker:9842243] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v86:[updateContainedRLE]
[UpdateTracker:9781593] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v60:[addHasEvent, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9786148] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v50:[updateIndirectRLE]
[UpdateTracker:9953750] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v93:[addHasEvent]
[UpdateTracker:9787374] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v45:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9785863] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v51:[updateIndirectRLE]
[UpdateTracker:9788058] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v44:[updateContainedRLE]
Referrals
(hasEvent)
[Pathway:R-HSA-156580] Phase II - Conjugation of compounds
(updatedInstance)
[UpdateTracker:9846983] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v82:[updateIndirectRLE]
[UpdateTracker:9788806] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v40:[updateContainedRLE]
[UpdateTracker:9784195] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v54:[addHasEvent, updateContainedRLE]
[UpdateTracker:9790400] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v33:[addHasEvent]
[UpdateTracker:9789480] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v38:[updateContainedPathway]
[UpdateTracker:9842243] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v86:[updateContainedRLE]
[UpdateTracker:9781593] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v60:[addHasEvent, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9786148] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v50:[updateIndirectRLE]
[UpdateTracker:9953750] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v93:[addHasEvent]
[UpdateTracker:9787374] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v45:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9785863] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v51:[updateIndirectRLE]
[UpdateTracker:9788058] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v44:[updateContainedRLE]
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