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Entries
2-acyl LPS is acylated to PS by LPSAT
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authored
[InstanceEdit:1602345] Williams, MG, 2011年09月14日
catalystActivity
[CatalystActivity:1524049] 2-acylglycerol-3-phosphate O-acyltransferase activity of LPSAT [endoplasmic reticulum membrane]
category
transition
compartment
[Compartment:12045] endoplasmic reticulum membrane
[Compartment:70101] cytosol
created
[InstanceEdit:1482525] Williams, MG, 2011年08月12日
dbId
1482691
displayName
2-acyl LPS is acylated to PS by LPSAT
edited
[InstanceEdit:1482514] Williams, MG, 2011年08月12日
eventOf
[Pathway:R-HSA-1482801] Acyl chain remodelling of PS - Homo sapiens
followingEvent
[Reaction:R-HSA-1482897] PS is hydrolyzed to 2-acyl LPS by PLA2[10] - Homo sapiens
[BlackBoxEvent:R-HSA-1483170] PS transports from the ER membrane to the IM membrane - Homo sapiens
[Reaction:R-HSA-1482776] PS is hydrolyzed to 1-acyl LPS by PLA2G2A - Homo sapiens
[Reaction:R-HSA-1482771] PS is hydrolyzed to 1-acyl LPS by PLA2[9] - Homo sapiens
input
[SimpleEntity:R-ALL-1498722] 2-acyl LPS [endoplasmic reticulum membrane]
[SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1482645] Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity
[LiteratureReference:429001] Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils
[LiteratureReference:1482687] Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2
maxDepth
1
modified
[InstanceEdit:11064438] Weiser, Joel, 2025年08月28日
name
2-acyl LPS is acylated to PS by LPSAT
orthologousEvent
[Reaction:R-PFA-1482691] 2-acyl LPS is acylated to PS by LPSAT - Plasmodium falciparum
[Reaction:R-DDI-1482691] 2-acyl LPS is acylated to PS by LPSAT - Dictyostelium discoideum
[Reaction:R-SCE-1482691] 2-acyl LPS is acylated to PS by LPSAT - Saccharomyces cerevisiae
[Reaction:R-SPO-1482691] 2-acyl LPS is acylated to PS by LPSAT - Schizosaccharomyces pombe
[Reaction:R-CFA-1482691] 2-acyl LPS is acylated to PS by LPSAT - Canis familiaris
[Reaction:R-MMU-1482691] 2-acyl LPS is acylated to PS by LPSAT - Mus musculus
[Reaction:R-CEL-1482691] 2-acyl LPS is acylated to PS by LPSAT - Caenorhabditis elegans
[Reaction:R-DME-1482691] 2-acyl LPS is acylated to PS by LPSAT - Drosophila melanogaster
[Reaction:R-GGA-1482691] 2-acyl LPS is acylated to PS by LPSAT - Gallus gallus
[Reaction:R-XTR-1482691] 2-acyl LPS is acylated to PS by LPSAT - Xenopus tropicalis
[Reaction:R-SSC-1482691] 2-acyl LPS is acylated to PS by LPSAT - Sus scrofa
[Reaction:R-BTA-1482691] 2-acyl LPS is acylated to PS by LPSAT - Bos taurus
[Reaction:R-RNO-1482691] 2-acyl LPS is acylated to PS by LPSAT - Rattus norvegicus
output
[SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
[SimpleEntity:R-ALL-1500646] PS [endoplasmic reticulum membrane]
precedingEvent
[Reaction:R-HSA-1482897] PS is hydrolyzed to 2-acyl LPS by PLA2[10] - Homo sapiens
releaseDate
2012年06月12日
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-1482691
summation
[Summation:1482607] At the endoplasmic reticulum (ER) membrane, lysophospholipid...
Referrals
(hasEvent)
[Pathway:R-HSA-1482801] Acyl chain remodelling of PS
(precedingEvent)
[BlackBoxEvent:R-HSA-1483170] PS transports from the ER membrane to the IM membrane
[Reaction:R-HSA-1482776] PS is hydrolyzed to 1-acyl LPS by PLA2G2A
[Reaction:R-HSA-1482771] PS is hydrolyzed to 1-acyl LPS by PLA2[9]
[Reaction:R-HSA-1482897] PS is hydrolyzed to 2-acyl LPS by PLA2[10]
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