Reactome Pathway Database

Schema > Reaction > Entries

tissue factor (TF) + factor VII (F7) -> TF:F7 complex Show undefined attributes

authored

[InstanceEdit:140579] D'Eustachio, P, 2004年08月24日 14:00:00

category binding

compartment

created [InstanceEdit:140579] D'Eustachio, P, 2004年08月24日 14:00:00

dbId 140783

displayName tissue factor (TF) + factor VII (F7) -> TF:F7 complex

eventOf

[Pathway:R-HSA-140834] Extrinsic Pathway of Fibrin Clot Formation - Homo sapiens

followingEvent

[Reaction:R-HSA-140777] factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

tissue factor (TF) + factor VII (F7) -> TF:F7 complex
formation of TF:F7 complex

orthologousEvent

output

[Complex:R-HSA-140775] TF:F7 [plasma membrane]

precedingEvent

[Reaction:R-HSA-140761] sequestered tissue factor -> tissue factor - Homo sapiens

regulatedBy

[PositiveRegulation:R-HSA-158643] Positive regulation by 'Ca2+ [extracellular region]'

regulationReference

[RegulationReference:9671760] Positive regulation by 'Ca2+ [extracellular region]' Characterization of factor VII association with tissue factor in solution. High and low affinity calcium binding sites in factor VII contribute to functionally distinct interactions

releaseDate 2004年10月27日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-140783

summation

[Summation:140784] This Reactome event describes binding of the cell surface-bo...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-140834] Extrinsic Pathway of Fibrin Clot Formation

(precedingEvent)

[Reaction:R-HSA-140777] factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst)

© 2025 Reactome

Cite Us!