Reactome Pathway Database

Schema > Complex > Entries

EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] Show undefined attributes

catalystActivities

[CatalystActivity:1306960] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane]

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:1306964] Orlic-Milacic, Marija, 2011年05月27日

dbId 1306961

displayName EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane]

hasComponent

inDisease false

includedLocation

[Compartment:70101] cytosol

inferredTo

isChimeric false

maxDepth 7

memberOf

[DefinedSet:R-HSA-2316432] Activator:PI3K [plasma membrane] - Homo sapiens

modified [InstanceEdit:2213009] Matthews, L, 2012年04月27日

name

EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K
PI3K:GRB2:GAB1:P-ERBB2:P-EGFR

producedByEvent

[Reaction:R-HSA-1306965] Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-1306961

updateTrackers

Referrals

(updatedInstance)

(normalEntity)

(physicalEntity)

[CatalystActivity:1306960] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane]

(output)

[Reaction:R-HSA-1306965] Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR

(hasMember)

[DefinedSet:R-HSA-2316432] Activator:PI3K [plasma membrane]

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