Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

EGFR G719C [plasma membrane] Show undefined attributes

candidateOf

[CandidateSet:R-HSA-1176052] Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane] - Homo sapiens

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:1177529] Orlic-Milacic, Marija, 2011年01月25日

crossReference

dbId 1177531

disease

displayName EGFR G719C [plasma membrane]

endCoordinate 1210

hasModifiedResidue

[ReplacedResidue:1177534] glycine 719 replaced with L-cysteine

inDisease true

literatureReference

[LiteratureReference:1169414] Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity

maxDepth 1

modified [InstanceEdit:3662293] Orlic-Milacic, M, 2013年06月06日

name

EGFR G719C
Epidermal Growth Factor Receptor G719C
EGFR Gly719Cys

referenceEntity [ReferenceGeneProduct:uniprot:P00533] UniProt:P00533 EGFR

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-1177531

startCoordinate 25

updateTrackers

[UpdateTracker:9888123] Update Tracker - [EntityWithAccessionedSequence:1177531] EGFR G719C [plasma membrane] - v46:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9888123] Update Tracker - [EntityWithAccessionedSequence:1177531] EGFR G719C [plasma membrane] - v46:[modifyName]

(hasCandidate)

[CandidateSet:R-HSA-1176052] Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane]

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