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Thrombin-activated PARs activate G12/13 Show undefined attributes

catalystActivity

[CatalystActivity:139932] G protein-coupled receptor activity of Thrombin-activated PARs [plasma membrane]

category transition

compartment

created [InstanceEdit:141659] de Bono, B, Pace, N.P., Farndale, R, 2004年09月25日 17:06:19

dbId 114552

displayName Thrombin-activated PARs activate G12/13

eventOf

[Pathway:R-HSA-456926] Thrombin signalling through proteinase activated receptors (PARs) - Homo sapiens

followingEvent

[Reaction:R-HSA-397891] Thrombin-activated PARs:G12/13 (active) dissociate - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

[LiteratureReference:428920] G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Thrombin-activated PARs activate G12/13
G12/13 activation by PAR

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-396941] Thrombin-activated PARs binds G-protein G12/13 - Homo sapiens

releaseDate 2004年10月27日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-114552

summation

[Summation:178828] PAR1, 3 and 4 have been shown to directly couple with G12/13...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-456926] Thrombin signalling through proteinase activated receptors (PARs)

(precedingEvent)

[Reaction:R-HSA-397891] Thrombin-activated PARs:G12/13 (active) dissociate

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