Reactome Pathway Database

Schema > Complex > Entries

MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm] Show undefined attributes

catalystActivities

[CatalystActivity:5649473] DNA N-glycosylase activity of MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm]

compartment

[Compartment:7660] nucleoplasm

consumedByEvent

[Reaction:R-HSA-110246] Cleavage of adenine mispaired with 8-oxoguanine by MUTYH - Homo sapiens

created [InstanceEdit:110175] Matthews, L, 2004年01月29日 08:00:00

dbId 110199

displayName MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm]

hasComponent

inDisease false

inferredTo

maxDepth 3

modified [InstanceEdit:9663830] Orlic-Milacic, Marija, 2019年10月15日

name

MUTYH:(8oxoG:Ade)-dsDNA
MYH glycosylase:adenine complex

producedByEvent

[Reaction:R-HSA-110237] MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-110199

updateTrackers

Referrals

(updatedInstance)

(normalEntity)

[EntityFunctionalStatus:9605336] loss_of_function of MUTYH LOF mutants:(8oxoG:Ade)-dsDNA [nucleoplasm]

(output)

[Reaction:R-HSA-110237] MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine

(input)

[Reaction:R-HSA-110246] Cleavage of adenine mispaired with 8-oxoguanine by MUTYH

(physicalEntity)

[CatalystActivity:5649473] DNA N-glycosylase activity of MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm]

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