Reactome Pathway Database

Schema > Complex > Entries

OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] Show undefined attributes

catalystActivities

[CatalystActivity:5643997] oxidized purine nucleobase lesion DNA N-glycosylase activity of OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm]

compartment

[Compartment:7660] nucleoplasm

consumedByEvent

[Reaction:R-HSA-110243] Excision of 8-oxoguanine by OGG1 glycosylase - Homo sapiens

created [InstanceEdit:110175] Matthews, L, 2004年01月29日 08:00:00

dbId 110185

displayName OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm]

hasComponent

inDisease false

inferredTo

maxDepth 2

modified [InstanceEdit:9663830] Orlic-Milacic, Marija, 2019年10月15日

name

OGG1:(8oxoG:Cyt)-dsDNA
OGG1:8-oxo guanine complex

producedByEvent

[Reaction:R-HSA-110235] OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-110185

updateTrackers

Referrals

(updatedInstance)

(normalEntity)

[EntityFunctionalStatus:9656302] loss_of_function of OGG1 mutants:(8oxoG:Cyt)-dsDNA [nucleoplasm]

(output)

[Reaction:R-HSA-110235] OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine

(input)

[Reaction:R-HSA-110243] Excision of 8-oxoguanine by OGG1 glycosylase

(physicalEntity)

[CatalystActivity:5643997] oxidized purine nucleobase lesion DNA N-glycosylase activity of OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm]

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