Reactome | SLC35B2,3 exchange cytosolic PAPS with Golgi PAP

catalystActivity

[CatalystActivity:10710881] 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity of SLC35B2,3 [Golgi membrane]

category transition

compartment

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10710883

displayName SLC35B2,3 exchange cytosolic PAPS with Golgi PAP

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-GGA-9940718] CHST10 sulfates matriglycan chain - Gallus gallus
[Reaction:R-GGA-9668023] TPST1,2 transfer SO4(2-) from PAPS to FVIII - Gallus gallus
[Reaction:R-GGA-8954262] TPST1,2 transfer SO4(2-) from PAPS to PODXL2 - Gallus gallus
[Reaction:R-GGA-2076419] HS6STs sulfate GlcN at C6 in heparan sulfate/heparin - Gallus gallus
[Reaction:R-GGA-2076508] HS2ST1 trimer sulfates IdoA at C2 in heparan sulfate - Gallus gallus
[Reaction:R-GGA-9941312] CHST15 transfers sulfate to (6-)GalNAc-4-sulfate - Gallus gallus
[Reaction:R-GGA-6786012] CHST4 transfers SO4(2-) from PAPS to Core 2 mucins - Gallus gallus
[Reaction:R-GGA-2046175] CHST1 transfers sulfate to Gal on keratan chain - Gallus gallus
[Reaction:R-GGA-2046222] CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain - Gallus gallus
[Reaction:R-GGA-2076611] HS3ST2-6 sulfate GlcN at C3 in heparan sulfate - Gallus gallus
[Reaction:R-GGA-2076383] HS3ST1 sulfates GlcN at C3 in heparan sulfate - Gallus gallus
[Reaction:R-GGA-2022860] NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) - Gallus gallus
[Reaction:R-GGA-2022063] CHST14 transfers SO4(2-) to GalNAc in dermatan or DS - Gallus gallus
[Reaction:R-GGA-2022061] Dermatan sulfate can be further sulfated on position 2 of iduronate - Gallus gallus
[Reaction:R-GGA-2018659] CHST15 transfers sulfate to (6-)GalNAc-4-sulfate - Gallus gallus
[Reaction:R-GGA-1971483] CHST11,12,13,9 transfer sulfate to (4-)GalNAc - Gallus gallus
[Reaction:R-GGA-2018682] CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains - Gallus gallus

goBiologicalProcess [GO_BiologicalProcess:5263389] 5'-adenylyl sulfate transmembrane transport

inferredFrom

[Reaction:R-HSA-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

SLC35B2,3 exchange cytosolic PAPS with Golgi PAP

output

precedingEvent

[Reaction:R-GGA-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Gallus gallus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-741449

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Reactome Pathway Database

Reactome Pathway Database

SLC35B2,3 exchange cytosolic PAPS with Golgi PAP Show undefined attributes

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