Reactome Pathway Database

Schema > Reaction > Entries

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ Show undefined attributes

catalystActivity

[CatalystActivity:10683986] 3-hydroxybutyrate dehydrogenase activity of BDH1 tetramer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10683999

displayName D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

eventOf

[Pathway:R-GGA-77108] Utilization of Ketone Bodies - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-GGA-74177] OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA - Gallus gallus

inferredFrom

[Reaction:R-HSA-73920] D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-73920

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-77108] Utilization of Ketone Bodies

(precedingEvent)

[Reaction:R-GGA-74177] OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA

(inferredTo)

[Reaction:R-HSA-73920] D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

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