Reactome Pathway Database

Schema > Reaction > Entries

DNA polymerases delta, epsilon or kappa bind the TC-NER site Show undefined attributes

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10747942

displayName DNA polymerases delta, epsilon or kappa bind the TC-NER site

eventOf

[Pathway:R-GGA-6782135] Dual incision in TC-NER - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

DNA polymerases delta, epsilon or kappa bind the TC-NER site

output

[Complex:R-GGA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]

precedingEvent

[Reaction:R-GGA-6782204] 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER - Gallus gallus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-6782211

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-6782135] Dual incision in TC-NER

(inferredTo)

[Reaction:R-HSA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site

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