Reactome Pathway Database

Schema > Reaction > Entries

NNT dimer transfers proton from NADPH to NAD+ Show undefined attributes

catalystActivity

[CatalystActivity:10709401] NAD(P)+ transhydrogenase (Si-specific) activity of NNT dimer [mitochondrial inner membrane]

category transition

compartment

[Compartment:5462] mitochondrion

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10709403

displayName NNT dimer transfers proton from NADPH to NAD+

eventOf

[Pathway:R-GGA-71403] Citric acid cycle (TCA cycle) - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-450971] NNT dimer transfers proton from NADPH to NAD+ - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

NNT dimer transfers proton from NADPH to NAD+
H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)

output

precedingEvent

[Reaction:R-GGA-450984] IDH2 dimer decarboxylates isocitrate - Gallus gallus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-450971

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-71403] Citric acid cycle (TCA cycle)

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-450971] NNT dimer transfers proton from NADPH to NAD+

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