Reactome Pathway Database

Schema > Reaction > Entries

Activated human JNKs migrate to nucleoplasm Show undefined attributes

category transition

compartment

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10709253

displayName Activated human JNKs migrate to nucleoplasm

eventOf

[Pathway:R-GGA-450321] JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 - Gallus gallus
[Pathway:R-GGA-2559580] Oxidative Stress Induced Senescence - Gallus gallus
[Pathway:R-GGA-2871796] FCERI mediated MAPK activation - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-450348] Activated human JNKs migrate to nucleoplasm - Homo sapiens

input

[DefinedSet:R-GGA-450226] p-MAPK8,9,10 [cytosol]

isInDisease false

isInferred true

maxDepth 1

name

Activated human JNKs migrate to nucleoplasm

output

[DefinedSet:R-GGA-450253] p-MAPK8,9,10 [nucleoplasm]

precedingEvent

[Reaction:R-GGA-168162] Phosphorylation of human JNKs by activated MKK4/MKK7 - Gallus gallus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-450348

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-450348] Activated human JNKs migrate to nucleoplasm

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