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Schema
>
Reaction
>
Entries
Activated JNK migrates to the nucleoplasm
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authored
[InstanceEdit:438031] Shamovsky, V, 2009年09月22日
category
transition
compartment
[Compartment:70101] cytosol
[Compartment:7660] nucleoplasm
[Compartment:13231] nuclear envelope
created
[InstanceEdit:438021] Shamovsky, V, 2009年09月22日
dbId
437995
displayName
Activated JNK migrates to the nucleoplasm
edited
[InstanceEdit:668815] Shamovsky, V, 2010年05月04日
eventOf
[Pathway:R-GGA-437986] Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation - Gallus gallus
followingEvent
[Reaction:R-GGA-438026] Activation and dimerization of c-JUN in the nucleus - Gallus gallus
inferredFrom
[Reaction:R-HSA-450348] Activated human JNKs migrate to nucleoplasm - Homo sapiens
input
[CandidateSet:R-GGA-437957] phosphorylated JNK homologs [cytosol]
isInDisease
false
isInferred
true
literatureReference
[LiteratureReference:208214] A novel mechanism of JNK1 activation. Nuclear translocation and activation of JNK1 during ischemia and reperfusion.
[LiteratureReference:500491] Evidence of functional modulation of the MEKK/JNK/cJun signaling cascade by the low density lipoprotein receptor-related protein (LRP)
[LiteratureReference:500486] Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
Activated JNK migrates to the nucleoplasm
output
[CandidateSet:R-GGA-438012] phosphorylated JNK homologs [nucleoplasm]
precedingEvent
[Reaction:R-GGA-438005] MKK4 phosphorylates JNK - Gallus gallus
releaseDate
2010年12月14日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:789693] D'Eustachio, P, 2010年05月23日
schemaClass
Reaction
species
[Species:49591] Gallus gallus
stId
R-GGA-437995
summation
[Summation:446230] Shortly after phosphorylation JNKs are translocated to nucl...
Referrals
(hasEvent)
[Pathway:R-GGA-437986] Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation
(precedingEvent)
[Reaction:R-GGA-438026] Activation and dimerization of c-JUN in the nucleus
(inferredTo)
[Reaction:R-HSA-450348] Activated human JNKs migrate to nucleoplasm
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