Reactome Pathway Database

Schema > Reaction > Entries

phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 Show undefined attributes

catalystActivity

[CatalystActivity:10704097] phytanoyl-CoA dioxygenase activity of PHYH:Fe++ [peroxisomal matrix]

category transition

compartment

[Compartment:17951] peroxisomal matrix

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10704099

displayName phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2

eventOf

[Pathway:R-GGA-389599] Alpha-oxidation of phytanate - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-GGA-389611] 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA - Gallus gallus

inferredFrom

[Reaction:R-HSA-389639] phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2
2-oxoglutarate + O2 + phytanoyl-CoA => 2-hydroxyphytanoyl-CoA + CO2 + succinate

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-389639

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-389599] Alpha-oxidation of phytanate

(precedingEvent)

[Reaction:R-GGA-389611] 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA

(inferredTo)

[Reaction:R-HSA-389639] phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2

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