Reactome Pathway Database

Schema > Reaction > Entries

PIP3 recruits PDPK1 to the membrane Show undefined attributes

category binding

compartment

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10730316

displayName PIP3 recruits PDPK1 to the membrane

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-GGA-2317314] AKT binds PDPK1 - Gallus gallus

inferredFrom

[Reaction:R-HSA-2316429] PIP3 recruits PDPK1 to the membrane - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PIP3 recruits PDPK1 to the membrane

output

[Complex:R-GGA-109697] PDPK1:PIP3 [plasma membrane]

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-2316429

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(precedingEvent)

[Reaction:R-GGA-2317314] AKT binds PDPK1

(inferredTo)

[Reaction:R-HSA-2316429] PIP3 recruits PDPK1 to the membrane

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