Reactome Pathway Database

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Negative Regulation of CDH1 Gene Transcription Show undefined attributes

created [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

dbId 10602760

displayName Negative Regulation of CDH1 Gene Transcription

eventOf

[Pathway:R-DRE-9764560] Regulation of CDH1 Gene Transcription - Danio rerio

evidenceType [EvidenceType:9965817] inferred by electronic annotation

hasDiagram false

hasEHLD false

hasEvent

[Reaction:R-DRE-9764932] PRC2 (EZH2) core complex methylates nucleosomes at CDH1 gene promoter - Danio rerio
[Reaction:R-DRE-9765788] TWIST1 recruits SETD8 to CDH1 gene promoter - Danio rerio
[Reaction:R-DRE-9764786] ZEB1 recruits SMARCA4 to CDH1 gene promoter - Danio rerio
[Reaction:R-DRE-9765791] ZEB1 recruits SETD8 to CDH1 gene promoter - Danio rerio
[Reaction:R-DRE-9765973] CTBP1,CTBP2 binds ZEB1 - Danio rerio

inferredFrom

[Pathway:R-HSA-9764725] Negative Regulation of CDH1 Gene Transcription - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Negative Regulation of CDH1 Gene Transcription

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:68323] Danio rerio

stId R-DRE-9764725

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DRE-9764560] Regulation of CDH1 Gene Transcription

(inferredTo)

[Pathway:R-HSA-9764725] Negative Regulation of CDH1 Gene Transcription

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