Reactome Pathway Database

Schema > Reaction > Entries

PNPLA5 hydrolyzes TAG Show undefined attributes

catalystActivity

[CatalystActivity:10588022] triacylglycerol lipase activity of PNPLA5 [cytosol]

category transition

compartment

created [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

dbId 10588024

displayName PNPLA5 hydrolyzes TAG

eventOf

[Pathway:R-DRE-163560] Triglyceride catabolism - Danio rerio

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-8848339] PNPLA5 hydrolyzes TAG - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PNPLA5 hydrolyzes TAG
a triacylglycerol + H2O => a diacylglycerol + a fatty acid + H(+)

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68323] Danio rerio

stId R-DRE-8848339

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DRE-163560] Triglyceride catabolism

(inferredTo)

[Reaction:R-HSA-8848339] PNPLA5 hydrolyzes TAG

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