Reactome Pathway Database

Schema > Reaction > Entries

AcCho is hydrolyzed to Cho and acetate by ACHE Show undefined attributes

catalystActivity

[CatalystActivity:10553784] acetylcholinesterase activity of Cholinesterase [plasma membrane]

category transition

compartment

created [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

dbId 10553788

displayName AcCho is hydrolyzed to Cho and acetate by ACHE

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-DRE-444433] Cho transports from the extracellular space to the cytosol - Danio rerio

goBiologicalProcess [GO_BiologicalProcess:19389] acetylcholine catabolic process

inferredFrom

[Reaction:R-HSA-372519] AcCho is hydrolyzed to Cho and acetate by ACHE - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

AcCho is hydrolyzed to Cho and acetate by ACHE
Acetylcholine clearance from synaptic cleft

output

regulatedBy

[NegativeRegulation:10553789] Negative regulation by 'ACHE:ACHEIs [plasma membrane]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68323] Danio rerio

stId R-DRE-372519

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(precedingEvent)

[Reaction:R-DRE-444433] Cho transports from the extracellular space to the cytosol

(inferredTo)

[Reaction:R-HSA-372519] AcCho is hydrolyzed to Cho and acetate by ACHE

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