Reactome Pathway Database

Schema > Reaction > Entries

NADK2 dimer phosphorylates NAD+ to NADP+ Show undefined attributes

catalystActivity

[CatalystActivity:10853930] NAD+ kinase activity of NADK2 dimer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10778922] Weiser, Joel, 2025年08月27日

dbId 10853932

displayName NADK2 dimer phosphorylates NAD+ to NADP+

eventOf

[Pathway:R-DME-196807] Nicotinate metabolism - Drosophila melanogaster

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-8955030] NADK2 dimer phosphorylates NAD+ to NADP+ - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

NADK2 dimer phosphorylates NAD+ to NADP+
NAD(+) + ATP => ADP + NADP(+) + H(+)

output

precedingEvent

[Reaction:R-DME-9938195] SLC25A51 mediates mitochondrial uptake of NAD+ - Drosophila melanogaster

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:56210] Drosophila melanogaster

stId R-DME-8955030

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DME-196807] Nicotinate metabolism

(inferredTo)

[Reaction:R-HSA-8955030] NADK2 dimer phosphorylates NAD+ to NADP+

© 2025 Reactome

Cite Us!