Reactome Pathway Database

Schema > Reaction > Entries

ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA Show undefined attributes

catalystActivity

[CatalystActivity:10799364] pristanoyl-CoA oxidase activity of ACOX2:FAD, ACOXL:FAD [peroxisomal matrix]

category transition

compartment

[Compartment:17951] peroxisomal matrix

created [InstanceEdit:10778922] Weiser, Joel, 2025年08月27日

dbId 10799366

displayName ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA

eventOf

[Pathway:R-DME-389887] Beta-oxidation of pristanoyl-CoA - Drosophila melanogaster

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-DME-389986] trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA - Drosophila melanogaster

inferredFrom

[Reaction:R-HSA-389889] ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA
(2S)-pristanoyl-CoA + O2 => (2E)-pristenoyl-CoA + H2O2
(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX2)

output

precedingEvent

[Reaction:R-DME-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Drosophila melanogaster

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:56210] Drosophila melanogaster

stId R-DME-389889

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DME-389887] Beta-oxidation of pristanoyl-CoA

(precedingEvent)

[Reaction:R-DME-389986] trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA

(inferredTo)

[Reaction:R-HSA-389889] ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA

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