Reactome Pathway Database

Schema > Reaction > Entries

3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP Show undefined attributes

catalystActivity

[CatalystActivity:10790124] aryl sulfotransferase activity of SULT dimers (T2) [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10778922] Weiser, Joel, 2025年08月27日

dbId 10790126

displayName 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP

eventOf

[Pathway:R-DME-156584] Cytosolic sulfonation of small molecules - Drosophila melanogaster

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-DME-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Drosophila melanogaster

inferredFrom

[Reaction:R-HSA-176474] 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP

output

precedingEvent

[Reaction:R-DME-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Drosophila melanogaster

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:56210] Drosophila melanogaster

stId R-DME-176474

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DME-156584] Cytosolic sulfonation of small molecules

(precedingEvent)

[Reaction:R-DME-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate

(inferredTo)

[Reaction:R-HSA-176474] 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP

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