Reactome Pathway Database

Schema > Complex > Entries

NFkB inhibitor:NFkB complex [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

consumedByEvent

[BlackBoxEvent:R-DME-9861486] PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus - Drosophila melanogaster
[Reaction:R-DME-202541] p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB - Drosophila melanogaster
[Reaction:R-DME-168140] Active IKK Complex phosphorylates NF-kappa-B inhibitor - Drosophila melanogaster
[Reaction:R-DME-9773803] Active IKBKB phosphorylates NF-kappa-B inhibitor - Drosophila melanogaster

created [InstanceEdit:10778922] Weiser, Joel, 2025年08月27日

dbId 10788891

displayName NFkB inhibitor:NFkB complex [cytosol]

hasComponent

inDisease false

inferredFrom

maxDepth 4

name

NFkB inhibitor:NFkB complex

producedByEvent

[Reaction:R-DME-9630923] NF-kappa-B inhibitor binds NF-kappa-B complex - Drosophila melanogaster

schemaClass Complex

species

[Species:56210] Drosophila melanogaster

stId R-DME-168130

summation

[Summation:9965818] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)

(inferredTo)

(output)

[Reaction:R-DME-9630923] NF-kappa-B inhibitor binds NF-kappa-B complex

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