Reactome Pathway Database

Schema > BlackBoxEvent > Entries

CHOL translocates from lysosome membrane to ER membrane Show undefined attributes

category omitted

compartment

created [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

dbId 10991567

displayName CHOL translocates from lysosome membrane to ER membrane

eventOf

[Pathway:R-DDI-8964038] LDL clearance - Dictyostelium discoideum

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-8876485] CHOL translocates from lysosome membrane to ER membrane - Homo sapiens

input

[Complex:R-DDI-8876475] NPC1:CHOL [lysosomal membrane]

isInDisease false

isInferred true

maxDepth 1

name

CHOL translocates from lysosome membrane to ER membrane

output

precedingEvent

[Reaction:R-DDI-8876484] NPC2 transfers CHOL to NPC1 - Dictyostelium discoideum

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:170941] Dictyostelium discoideum

stId R-DDI-8876485

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DDI-8964038] LDL clearance

(inferredTo)

[BlackBoxEvent:R-HSA-8876485] CHOL translocates from lysosome membrane to ER membrane

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