Reactome Pathway Database

Schema > Reaction > Entries

OSBPs transport 25OH-CHOL from ER membrane to plasma membrane Show undefined attributes

catalystActivity

[CatalystActivity:10989851] sterol transfer activity of OSBPs [cytosol]

category transition

compartment

created [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

dbId 10989853

displayName OSBPs transport 25OH-CHOL from ER membrane to plasma membrane

eventOf

[Pathway:R-DDI-192105] Synthesis of bile acids and bile salts - Dictyostelium discoideum

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-DDI-1676124] PI4P is dephosphorylated to PI by SACM1L at the ER membrane - Dictyostelium discoideum

inferredFrom

[Reaction:R-HSA-8867667] OSBPs transport 25OH-CHOL from ER membrane to plasma membrane - Homo sapiens

input

[SimpleEntity:R-ALL-8868399] 25OH-CHOL [endoplasmic reticulum membrane]

isInDisease false

isInferred true

maxDepth 1

name

OSBPs transport 25OH-CHOL from ER membrane to plasma membrane

output

[SimpleEntity:R-ALL-8868400] 25OH-CHOL [plasma membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:170941] Dictyostelium discoideum

stId R-DDI-8867667

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DDI-192105] Synthesis of bile acids and bile salts

(precedingEvent)

[Reaction:R-DDI-1676124] PI4P is dephosphorylated to PI by SACM1L at the ER membrane

(inferredTo)

[Reaction:R-HSA-8867667] OSBPs transport 25OH-CHOL from ER membrane to plasma membrane

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