Reactome Pathway Database

Schema > Reaction > Entries

AKR1B15 reduces EST17b to E1 Show undefined attributes

catalystActivity

[CatalystActivity:10981851] estradiol 17-beta-dehydrogenase [NAD(P)+] activity of AKR1B15 [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

dbId 10981853

displayName AKR1B15 reduces EST17b to E1

eventOf

[Pathway:R-DDI-193144] Estrogen biosynthesis - Dictyostelium discoideum

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-5696822] AKR1B15 reduces EST17b to E1 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

AKR1B15 reduces EST17b to E1

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:170941] Dictyostelium discoideum

stId R-DDI-5696822

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DDI-193144] Estrogen biosynthesis

(inferredTo)

[Reaction:R-HSA-5696822] AKR1B15 reduces EST17b to E1

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