Reactome Pathway Database

Schema > Reaction > Entries

Addition of the first glucose to the N-glycan precursor by ALG6 Show undefined attributes

catalystActivity

[CatalystActivity:10963673] dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity of ALG6 [endoplasmic reticulum membrane]

category transition

compartment

[Compartment:17957] endoplasmic reticulum lumen

created [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

dbId 10963675

displayName Addition of the first glucose to the N-glycan precursor by ALG6

eventOf

[Pathway:R-DDI-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein - Dictyostelium discoideum

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-DDI-446189] Addition of a second glucose to the N-glycan precursor by ALG8 - Dictyostelium discoideum

inferredFrom

[Reaction:R-HSA-446202] Addition of the first glucose to the N-glycan precursor by ALG6 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Addition of the first glucose to the N-glycan precursor by ALG6

output

precedingEvent

[Reaction:R-DDI-446216] ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 - Dictyostelium discoideum

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:170941] Dictyostelium discoideum

stId R-DDI-446202

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DDI-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

(precedingEvent)

[Reaction:R-DDI-446189] Addition of a second glucose to the N-glycan precursor by ALG8

(inferredTo)

[Reaction:R-HSA-446202] Addition of the first glucose to the N-glycan precursor by ALG6

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