Reactome Pathway Database

Schema > Reaction > Entries

Recruitment of LIG3:XRCC1 complex to the site of repair by POLB Show undefined attributes

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

dbId 10954381

displayName Recruitment of LIG3:XRCC1 complex to the site of repair by POLB

eventOf

[Pathway:R-DDI-110381] Resolution of AP sites via the single-nucleotide replacement pathway - Dictyostelium discoideum

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-DDI-73932] Resynthesis of excised residue by POLB - Dictyostelium discoideum

inferredFrom

[Reaction:R-HSA-110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Recruitment of LIG3:XRCC1 complex to the site of repair by POLB

output

[Complex:R-DDI-110339] LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm]

precedingEvent

[Reaction:R-DDI-110375] Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break - Dictyostelium discoideum

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:170941] Dictyostelium discoideum

stId R-DDI-110376

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DDI-110381] Resolution of AP sites via the single-nucleotide replacement pathway

(precedingEvent)

[Reaction:R-DDI-73932] Resynthesis of excised residue by POLB

(inferredTo)

[Reaction:R-HSA-110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB

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