Reactome Pathway Database

Schema > Reaction > Entries

K63-Ub-polyLacNac-Glycosylated CD274 transport to plasma membrane Show undefined attributes

category transition

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10304591

displayName K63-Ub-polyLacNac-Glycosylated CD274 transport to plasma membrane

eventOf

[Pathway:R-CFA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9931288] K63-Ub-polyLacNac-Glycosylated CD274 transport to plasma membrane - Homo sapiens

input

[EntityWithAccessionedSequence:R-CFA-9931435] PDL1 [Golgi membrane]

isInDisease false

isInferred true

maxDepth 1

name

K63-Ub-polyLacNac-Glycosylated CD274 transport to plasma membrane

output

[EntityWithAccessionedSequence:R-CFA-9931307] PDL1 [plasma membrane]

precedingEvent

[Reaction:R-CFA-9931430] MIB2-mediated K63-ubiquitination of CD274 - Canis familiaris

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-9931288

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane

(inferredTo)

[Reaction:R-HSA-9931288] K63-Ub-polyLacNac-Glycosylated CD274 transport to plasma membrane

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