Reactome Pathway Database

Schema > Reaction > Entries

FAM83B, (FAM83A, FAM83D) bind EGFR Show undefined attributes

category binding

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10303133

displayName FAM83B, (FAM83A, FAM83D) bind EGFR

eventOf

[Pathway:R-CFA-177929] Signaling by EGFR - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-CFA-177934] EGFR autophosphorylation - Canis familiaris

goBiologicalProcess [GO_BiologicalProcess:24608] positive regulation of epidermal growth factor receptor signaling pathway

inferredFrom

[Reaction:R-HSA-9851407] FAM83B, (FAM83A, FAM83D) bind EGFR - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

FAM83B, (FAM83A, FAM83D) bind EGFR

output

[Complex:R-CFA-9851427] EGFR:FAM83B,(FAM83A, FAM83D) [plasma membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-9851407

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-177929] Signaling by EGFR

(precedingEvent)

[Reaction:R-CFA-177934] EGFR autophosphorylation

(inferredTo)

[Reaction:R-HSA-9851407] FAM83B, (FAM83A, FAM83D) bind EGFR

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