Reactome Pathway Database

Schema > BlackBoxEvent > Entries

JAK2 phosphorylation Show undefined attributes

category omitted

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10238863

displayName JAK2 phosphorylation

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-982810] JAK2 phosphorylation - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

JAK2 phosphorylation

output

precedingEvent

[BlackBoxEvent:R-CFA-1671687] PRLR activation - Canis familiaris

regulatedBy

[PositiveRegulation:10238864] Positive regulation by 'PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane]'

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:49646] Canis familiaris

stId R-CFA-982810

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(inferredTo)

[BlackBoxEvent:R-HSA-982810] JAK2 phosphorylation

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