Reactome Pathway Database

Schema > Reaction > Entries

Recruitment of SHC1 is mediated by Y593 of the common beta chain Show undefined attributes

category transition

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10236381

displayName Recruitment of SHC1 is mediated by Y593 of the common beta chain

eventOf

[Pathway:R-CFA-512988] Interleukin-3, Interleukin-5 and GM-CSF signaling - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Recruitment of SHC1 is mediated by Y593 of the common beta chain

output

[DefinedSet:R-CFA-913458] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]

precedingEvent

[Reaction:R-CFA-879907] Tyrosine kinases phosphorylate the receptor - Canis familiaris

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-879934

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-512988] Interleukin-3, Interleukin-5 and GM-CSF signaling

(inferredTo)

[Reaction:R-HSA-879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain

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