Reactome Pathway Database

Schema > Reaction > Entries

Caspase-mediated cleavage of PKC theta Show undefined attributes

catalystActivity

[CatalystActivity:10219496] cysteine-type endopeptidase activity of Caspase-3 [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10219508

displayName Caspase-mediated cleavage of PKC theta

eventOf

[Pathway:R-CFA-111465] Apoptotic cleavage of cellular proteins - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-201603] Caspase-mediated cleavage of PKC theta - Homo sapiens

input

[EntityWithAccessionedSequence:R-CFA-58216] PRKCQ [cytosol]

isInDisease false

isInferred true

maxDepth 1

name

Caspase-mediated cleavage of PKC theta

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-201603

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-111465] Apoptotic cleavage of cellular proteins

(inferredTo)

[Reaction:R-HSA-201603] Caspase-mediated cleavage of PKC theta

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