Reactome Pathway Database

Schema > Reaction > Entries

SHC1 binds P-ERBB4 isoform dimers Show undefined attributes

category binding

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10242020

displayName SHC1 binds P-ERBB4 isoform dimers

eventOf

[Pathway:R-CFA-1250347] SHC1 events in ERBB4 signaling - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-CFA-1250348] Phosphorylation of SHC1 by ERBB4 homodimers - Canis familiaris

inferredFrom

[Reaction:R-HSA-1250357] SHC1 binds P-ERBB4 isoform dimers - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

SHC1 binds P-ERBB4 isoform dimers

output

[Complex:R-CFA-1250359] SHC1:p-ERBB4 [plasma membrane]

precedingEvent

[Reaction:R-CFA-1250315] Trans-autophosphorylation of ERBB4 homodimers - Canis familiaris

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-1250357

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-1250347] SHC1 events in ERBB4 signaling

(precedingEvent)

[Reaction:R-CFA-1250348] Phosphorylation of SHC1 by ERBB4 homodimers

(inferredTo)

[Reaction:R-HSA-1250357] SHC1 binds P-ERBB4 isoform dimers

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