Reactome Pathway Database

Schema > Reaction > Entries

(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H Show undefined attributes

catalystActivity

[CatalystActivity:10874221] (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity of HADH dimer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

dbId 10874223

displayName (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H

eventOf

[Pathway:R-CEL-77310] Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA - Caenorhabditis elegans

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-CEL-77309] 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA - Caenorhabditis elegans

inferredFrom

[Reaction:R-HSA-77254] (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H

output

precedingEvent

[Reaction:R-CEL-77256] 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA - Caenorhabditis elegans

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68320] Caenorhabditis elegans

stId R-CEL-77254

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CEL-77310] Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA

(precedingEvent)

[Reaction:R-CEL-77309] 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA

(inferredTo)

[Reaction:R-HSA-77254] (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H

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