Reactome Pathway Database

Schema > Reaction > Entries

DHCR7 reduces 7-dehydroCHOL to CHOL Show undefined attributes

catalystActivity

[CatalystActivity:10879996] 7-dehydrocholesterol reductase activity of DHCR7 [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

dbId 10930369

displayName DHCR7 reduces 7-dehydroCHOL to CHOL

eventOf

[Pathway:R-CEL-6807062] Cholesterol biosynthesis via lathosterol - Caenorhabditis elegans

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-CEL-5250531] ARV1 transports CHOL from ER membrane to plasma membrane - Caenorhabditis elegans

inferredFrom

[Reaction:R-HSA-6807055] DHCR7 reduces 7-dehydroCHOL to CHOL - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

DHCR7 reduces 7-dehydroCHOL to CHOL
7-dehydrocholesterol + NADPH + H(+) => cholesterol + NADP(+)

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68320] Caenorhabditis elegans

stId R-CEL-6807055

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)

[Reaction:R-CEL-5250531] ARV1 transports CHOL from ER membrane to plasma membrane

(hasEvent)

[Pathway:R-CEL-6807062] Cholesterol biosynthesis via lathosterol

(inferredTo)

[Reaction:R-HSA-6807055] DHCR7 reduces 7-dehydroCHOL to CHOL

© 2025 Reactome

Cite Us!