Reactome Pathway Database

Schema > Reaction > Entries

Cleavage of collagen VII NC2 region by BMP1 Show undefined attributes

catalystActivity

[CatalystActivity:10909811] serine-type endopeptidase activity of Collagen type VII NC2 proteinases [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

dbId 10909813

displayName Cleavage of collagen VII NC2 region by BMP1

eventOf

[Pathway:R-CEL-2214320] Anchoring fibril formation - Caenorhabditis elegans

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Polymerisation:R-CEL-2213195] Formation of anchoring fibrils - Caenorhabditis elegans

inferredFrom

[Reaction:R-HSA-2214330] Cleavage of collagen VII NC2 region by BMP1 - Homo sapiens

input

[Complex:R-CEL-2127449] Collagen type VII hexamer [extracellular region]

isInDisease false

isInferred true

maxDepth 1

name

Cleavage of collagen VII NC2 region by BMP1

output

precedingEvent

[Reaction:R-CEL-2214324] Collagen type VII dimerization - Caenorhabditis elegans

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68320] Caenorhabditis elegans

stId R-CEL-2214330

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CEL-2214320] Anchoring fibril formation

(precedingEvent)

[Polymerisation:R-CEL-2213195] Formation of anchoring fibrils

(inferredTo)

[Reaction:R-HSA-2214330] Cleavage of collagen VII NC2 region by BMP1

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