Reactome Pathway Database

Schema > Reaction > Entries

Activation of proMMP7 by MMP3 Show undefined attributes

catalystActivity

[CatalystActivity:10902630] serine-type endopeptidase activity of MMP3, CTSK, CTSL2 [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

dbId 10902632

displayName Activation of proMMP7 by MMP3

eventOf

[Pathway:R-CEL-1592389] Activation of Matrix Metalloproteinases - Caenorhabditis elegans

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-1592362] Activation of proMMP7 by MMP3 - Homo sapiens

input

[DefinedSet:R-CEL-1604734-7] Homologues of MMP7(18-267) [extracellular region]

isInDisease false

isInferred true

maxDepth 1

name

Activation of proMMP7 by MMP3

output

precedingEvent

[Reaction:R-CEL-1604731] Autocatalytic activation of MMP3 - Caenorhabditis elegans

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68320] Caenorhabditis elegans

stId R-CEL-1592362

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CEL-1592389] Activation of Matrix Metalloproteinases

(inferredTo)

[Reaction:R-HSA-1592362] Activation of proMMP7 by MMP3

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