Reactome Pathway Database

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TRAF6-mediated induction of TAK1 complex within TLR4 complex Show undefined attributes

compartment

created [InstanceEdit:10309703] Weiser, Joel, 2025年08月27日

dbId 10422439

displayName TRAF6-mediated induction of TAK1 complex within TLR4 complex

eventOf

[Pathway:R-BTA-937061] TRIF (TICAM1)-mediated TLR4 signaling - Bos taurus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:20248] canonical NF-kappaB signal transduction

hasDiagram false

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-937072] TRAF6-mediated induction of TAK1 complex within TLR4 complex - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

TRAF6-mediated induction of TAK1 complex within TLR4 complex

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48898] Bos taurus

stId R-BTA-937072

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-BTA-937061] TRIF (TICAM1)-mediated TLR4 signaling

(inferredTo)

[Pathway:R-HSA-937072] TRAF6-mediated induction of TAK1 complex within TLR4 complex

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