Reactome Pathway Database

Schema > Reaction > Entries

glutamate + acetyl CoA => N-acetyl glutamate + CoA Show undefined attributes

catalystActivity

[CatalystActivity:10311331] L-glutamate N-acetyltransferase activity of NAGS(19-534) dimer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10309703] Weiser, Joel, 2025年08月27日

dbId 10311333

displayName glutamate + acetyl CoA => N-acetyl glutamate + CoA

eventOf

[Pathway:R-BTA-70635] Urea cycle - Bos taurus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-BTA-70555] 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] - Bos taurus

inferredFrom

[Reaction:R-HSA-70542] glutamate + acetyl CoA => N-acetyl glutamate + CoA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

glutamate + acetyl CoA => N-acetyl glutamate + CoA

output

regulatedBy

[PositiveRegulation:R-HSA-70543] Positive regulation by 'L-Arg [mitochondrial matrix]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48898] Bos taurus

stId R-BTA-70542

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-BTA-70635] Urea cycle

(precedingEvent)

[Reaction:R-BTA-70555] 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]

(inferredTo)

[Reaction:R-HSA-70542] glutamate + acetyl CoA => N-acetyl glutamate + CoA

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