Reactome Pathway Database

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RAF activation Show undefined attributes

created [InstanceEdit:10309703] Weiser, Joel, 2025年08月27日

dbId 10423317

displayName RAF activation

eventOf

[Pathway:R-BTA-5673001] RAF/MAP kinase cascade - Bos taurus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

hasDiagram false

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-5673000] RAF activation - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

RAF activation

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48898] Bos taurus

stId R-BTA-5673000

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-BTA-5673001] RAF/MAP kinase cascade

(inferredTo)

[Pathway:R-HSA-5673000] RAF activation

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