Reactome Pathway Database

Schema > Reaction > Entries

SMURF1/2 dissociates from ub-PTCH1 Show undefined attributes

category dissociation

compartment

[Compartment:261122] ciliary membrane

created [InstanceEdit:10309703] Weiser, Joel, 2025年08月27日

dbId 10380719

displayName SMURF1/2 dissociates from ub-PTCH1

eventOf

[Pathway:R-BTA-5632684] Hedgehog 'on' state - Bos taurus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[BlackBoxEvent:R-BTA-5632677] PTCH is internalized - Bos taurus

inferredFrom

[Reaction:R-HSA-5635865] SMURF1/2 dissociates from ub-PTCH1 - Homo sapiens

input

[Complex:R-BTA-5632582] ub-PTCH1:SMURF [ciliary membrane]

isInDisease false

isInferred true

maxDepth 1

name

SMURF1/2 dissociates from ub-PTCH1

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48898] Bos taurus

stId R-BTA-5635865

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-BTA-5632684] Hedgehog 'on' state

(precedingEvent)

[BlackBoxEvent:R-BTA-5632677] PTCH is internalized

(inferredTo)

[Reaction:R-HSA-5635865] SMURF1/2 dissociates from ub-PTCH1

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