Reactome Pathway Database

Schema > Reaction > Entries

G3P is acylated to 1-acyl LPA by AGPAT6 Show undefined attributes

catalystActivity

[CatalystActivity:10345461] glycerol-3-phosphate O-acyltransferase activity of AGPAT6 [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10309703] Weiser, Joel, 2025年08月27日

dbId 10345463

displayName G3P is acylated to 1-acyl LPA by AGPAT6

eventOf

[Pathway:R-BTA-1483166] Synthesis of PA - Bos taurus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-BTA-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) - Bos taurus

inferredFrom

[Reaction:R-HSA-549112] G3P is acylated to 1-acyl LPA by AGPAT6 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

G3P is acylated to 1-acyl LPA by AGPAT6
glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated]
Conversion of glycerol-3-phosphate to lysophosphatidic acid

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48898] Bos taurus

stId R-BTA-549112

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-BTA-1483166] Synthesis of PA

(precedingEvent)

[Reaction:R-BTA-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT)

(inferredTo)

[Reaction:R-HSA-549112] G3P is acylated to 1-acyl LPA by AGPAT6

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