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Schema
>
Complex
>
Entries
ERCC1:ERCC4 [nucleoplasm]
Show undefined attributes
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catalystActivities
[CatalystActivity:10384620] DNA endonuclease activity of ERCC1:ERCC4 [nucleoplasm]
compartment
[Compartment:7660] nucleoplasm
componentOf
[Complex:R-BTA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] - Bos taurus
[Complex:R-BTA-6782142] TC-NER incision complex [nucleoplasm] - Bos taurus
[Complex:R-BTA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Bos taurus
[Complex:R-BTA-6785734] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] - Bos taurus
consumedByEvent
[Reaction:R-BTA-5690991] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER - Bos taurus
[Reaction:R-BTA-6782141] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER - Bos taurus
[Reaction:R-BTA-6785732] DNA nucleases bind monoubiquitinated ID2 complex - Bos taurus
created
[InstanceEdit:10309703] Weiser, Joel, 2025年08月27日
dbId
10317174
displayName
ERCC1:ERCC4 [nucleoplasm]
hasComponent
[EntityWithAccessionedSequence:R-BTA-54427] ERCC1 [nucleoplasm]
[EntityWithAccessionedSequence:R-BTA-67445] ERCC4 [nucleoplasm]
inDisease
false
inferredFrom
[Complex:R-HSA-109943] ERCC1:ERCC4 [nucleoplasm] - Homo sapiens
maxDepth
2
name
ERCC1:ERCC4
producedByEvent
[Reaction:R-BTA-6782224] 3' incision by ERCC5 (XPG) in TC-NER - Bos taurus
[Reaction:R-BTA-109955] Formation of ERCC1:XPF heterodimeric complex - Bos taurus
[BlackBoxEvent:R-BTA-6785986] DNA nucleases unhook the interstrand crosslink (ICL) - Bos taurus
[Reaction:R-BTA-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER - Bos taurus
schemaClass
Complex
species
[Species:48898] Bos taurus
stId
R-BTA-109943
summation
[Summation:9965818] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Referrals
(output)
[BlackBoxEvent:R-BTA-6785986] DNA nucleases unhook the interstrand crosslink (ICL)
[Reaction:R-BTA-6782224] 3' incision by ERCC5 (XPG) in TC-NER
[Reaction:R-BTA-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER
[Reaction:R-BTA-109955] Formation of ERCC1:XPF heterodimeric complex
(input)
[Reaction:R-BTA-6785732] DNA nucleases bind monoubiquitinated ID2 complex
[Reaction:R-BTA-6782141] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
[Reaction:R-BTA-5690991] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER
(hasComponent)
[Complex:R-BTA-6785734] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm]
[Complex:R-BTA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
[Complex:R-BTA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm]
[Complex:R-BTA-6782142] TC-NER incision complex [nucleoplasm]
[Complex:R-BTA-5691046] GG-NER incision complex:Open bubble dsDNA [nucleoplasm]
[Complex:R-BTA-5691059] GG-NER incision complex:5'-incised damaged DNA [nucleoplasm]
[Complex:R-BTA-5690214] GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
(activeUnit)
[CatalystActivity:10388507] DNA endonuclease activity of TC-NER incision complex [nucleoplasm]
[CatalystActivity:10386237] endonuclease activity of GG-NER incision complex:Open bubble dsDNA [nucleoplasm]
(physicalEntity)
[CatalystActivity:10384620] DNA endonuclease activity of ERCC1:ERCC4 [nucleoplasm]
(inferredTo)
[Complex:R-HSA-109943] ERCC1:ERCC4 [nucleoplasm]
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